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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b61782eb9a137f16fa70de1a7e02345b466ae4c40862c193720134c2da98fc3' 
  AND token = 'WK7tF9O4a3AIi4sx6+bi2gdTv9IA4i8smC+BO8iitmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}