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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ce9d8a0dce2b55412d2cf6d107d992a623cabab88334a994a74e6f6c8c550c7' 
  AND token = 'P7w7vQHkiByKb7TbGLonqmLaiwhZbv4MN6mJ54FDK2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}