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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0adc80d2e66264c138c0714383a0d1cba239ff211b42a329beaf831731901a85' 
  AND token = 'gFwYdLkDS/u6oe7jdoZ5kE4QsN+4JC1Nm05Pi62bhfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}