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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a653fb3f02429413727c517fa53658c20a14a07caf76a3d115f4af30aa506c6e' 
  AND token = 'tM4SMYz3+1iU9TofqcmYkvB3X6TB8lO0WQeNEzZb/3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}