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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '863f1750b5c9ca0572e52ac8835a39bfd6275aa5648fc1f73d0741813dc40c64' 
  AND token = '0dvJmQJqM7EGOIYWvQYGEVYGcYiHtXgtqiqsLJSJ4Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}