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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '487fb7df7ece59447a140bd02edba75ea697fa16b842b327f078c680c22d57e2' 
  AND token = 'EhNktoVhk5ebvqJ79L+Q65tmNiuWI9Jp9GxlTYCqhKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}