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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b18ca777c8125e4be488e89ebc5d760b87050d833b0268bbf92b0f5ab0f77740' 
  AND token = 'ruBdCCTRinkUL40w85AdRFLlQjIrrEMAi5xzqf5G6gA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}