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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3d548a0f1b7b5c94ca0dfd4dd428134111f197929b0e5a0bbc427bc825f329c' 
  AND token = 'tNTaYWAiuKFyCpK4+TWbCR7UW7HAHWbSKriRARYsGJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}