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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e55ed0239a6d5c6f0efa039d5ab8db2227507495e9d891b531bdb96911dca844' 
  AND token = 'qXeh4v3dzrmvUKM7A54mezbz6XcYpn07bkBBY7eXEZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}