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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '144f5127a1693bafa6ee7819b41c3c54525fc674a8a0b8ef0373611dd246b677' 
  AND token = 'QjLrdOqHEHQXn1IaB2OnDz5ao5/hjjQXyxMLKOBEg0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}