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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d60e3c28ff37f6b8282f8d8daf040b96f0e5fe2d0473aef59a158174b77530f' 
  AND token = 'L0rSoc/fFreo8AFJR6pSl+EQv/NFKBQ1dHnQsNqteaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}