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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce438e0d8cef13535910a61d30538e8db46356169f54c93ad271f452d3a47b7d' 
  AND token = '2s82KGLvIk4Cf024xQDC0M9D24czCnoz02T4ZWeq80A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}