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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14ecef61f48ae8ee2f33fabf4e4a68acb20f5f397c94d33ec5e7fa64f93e5364' 
  AND token = '/68ZR0JZymclSbUjskWlL5MfpHMFQ0tCBXGpI6HiywM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}