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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df9979bbef62997e630f686f6e1b5321f79b2a274baee35762d4e0baaaee6d9' 
  AND token = 'G8qIRNf1D4IVy1j21yZdtap9AWfLX5htb5S3EiuKsBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}