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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aef1065e4b8b804159aa4d71bb6d2b889a3b83ca296404f597f7fe85d07b3944' 
  AND token = 'kwl0W87Js0lwm0dkWzV0pNxUWRWcGqzAdfJu5A2h5tE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}