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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc13ce926bc06142fa7456ddd22096c311a99143c438a6a1828ed88b08e2e6f6' 
  AND token = 'HkEg253x/bwWpFm+SJEN5UnGn+xd4utkZ99wb2uJb/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}