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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43dc8c58cb8d2ff316a4886dd536d4a3772b837a7831ca32903c5d500824aa3d' 
  AND token = 'yGvh1++l1ZH1u9WaNLv1dX8eFQw9K/OVhd5bPkJMEPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}