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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5ce7b29646b4343ef5412559bd9aceb03c872d909f6c401e500a88b6d331f4f' 
  AND token = '2mI9aW/1ooxg3WeyFCXiwsaEevldkyrQz2fAuDczBgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}