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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd05892718065180d86bf46b390aedf602d95151d905b32cd55db3224ca690d5b' 
  AND token = '1A42cveanxtP/4qD0rHyXmlL7ieOjIopiVkjuwO1RWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}