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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b0d6cafa6ab9656cb9cf613e13b0580e299b02f4159807aa7553a3b3b15c0af' 
  AND token = 'yNSjWITvx2zLvvOZJaPW3l7rwuOJ0uMYfgDXd1f5ZyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}