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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b2b59de984b51168651b96dcd5f545fc15d44837603d581787e50cd5489de2' 
  AND token = 'hiSxriyI2c3rXa+7N4k1frWv169aMlfpTB/KEp8PC1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}