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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '738f2e00eb851f8759f19455a9d18a13e9964539a66663732e873e1fb366872c' 
  AND token = '2IrmMaXigucu7OFE9W+wKPCg9kL2ey2PLyVWYRE2HdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}