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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aca9c0eec9be7f24b7e7cf0e1a266826f4fe6b4733aed9b55fcb7d3622c664c6' 
  AND token = 'AcdCVig6wPekHIlbEGy/vLbqdHEekNhGrAVjxh8K6aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}