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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a2fd29d66e4527477b92d7819a31d6532f7baee07c163bacee7c1643cf7c058' 
  AND token = 'X61UIiirXzXiPh1aJcHjDJfg73j+wRaCHYPnbGbBYrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}