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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fed999624f1aea606ba044c8e032fcb173b387cad4131c707eb5370034b23224' 
  AND token = 'AdtkWlbYc3aknTy4/+qnCt8pxJ6skyqjYFzSyfkdGDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}