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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50eb7a0384df68e01571b470ec45ea5d69f791e10f19d14fd5382c3d4d17c48f' 
  AND token = '1pwGrh06BTMPyvcR+VZEeoYLWLUBEhdeRmc6Yx54/Ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}