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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1108ff2f4969802c545e20b8bb99d6fef78f0c7a7f31c8123b794c53e1ee49ac' 
  AND token = 'TUorQNIJh3VYJL3S8nSa/aMO0vvEFuWPoO9hGGetnSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}