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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaca334b66d8a53bd1222a03cf4469a3a063ae95c68264cb3de567657c7ae950' 
  AND token = 'rVm4pFPYKDRKeiR5VBE0beV9YLQGz4vQeOFp8pWIhyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}