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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a12f2ca757979e495b7cbd74b37edfac4019b8c345397e0de550ab0bb4e15603' 
  AND token = 'xA5/R5b6hmzFOXsharLRMlVQcu+mrRf7Le5btWCNRfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}