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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a6ad2f72cd7f9b77194233d2c6b2b34293eb399edb22077fa840b75424a313d' 
  AND token = 'Lc4DXQpQ+5cfQV7brOMZ++BceX4TTl325rMGDyS4Djo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}