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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a973a8b037b99b253b5b3e4dfd85705d3e4e1c6727de713d8effe0910c53f018' 
  AND token = 'JrUBS1EdgcrG/qMVb2zwbwNf396DmW3p+tsCxcCLuXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}