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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f964586fa87978e0670c58f4db79c6e5a0f799839a501dd851d202a4793c165' 
  AND token = 'DUoGVRHmZ1Z5ZRHhqXrp+b2HYHLyaCpwCxoulyZ82Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}