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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd57e8f11368b74fbb96c622fa995c36ea6bac7d10c4a8eea148641ad9271c3a4' 
  AND token = '8pZD1XXbOo7jWKXOwr4zrhcnaLxmIVluYon1nb4G+V8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}