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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc4419ea9dbee2595c03943b4143c3f098fddd9c6865e8aab967709dff11f410' 
  AND token = '/7JlWvAlUsez2izLp+uHqclz3WAXA+OnFOMiA3NZuAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}