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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ede4e4757bb536e049a209cd57494ec62dbf6758fb597d0c61968781016cc9' 
  AND token = 'yz0eGOBoRs/B8R2T6ULxYLURy0mXpa87R0O8aahSlyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}