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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc24127fb630ca8121fd336327a4b0b09f6b520694035a7f53cfd37d8804aa4' 
  AND token = 'u/lc6M3+E8kytkH3pjQ6B3id+1kM+VhEJ9RjN5JeQAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}