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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f14e17d74722ad8c443f7552ae16bb41c737557500801cb4c7a1f4dc663aad2' 
  AND token = 'bB4kVrwOVS9m4Q+2hs79pYa/eOfJRvxiCbv2zzTyJJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}