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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efad012feefcd2be6035537fc78663a953b90761a1872513967f99d8c78c17bc' 
  AND token = 'wAxXsgxGSUuRDez0V1H3AFoG+jaOplLeUYABvfl6mfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}