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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a72daef62518e0914b784abc1874ea1fb22994d684ec7c8600cb0dbfdff77f0' 
  AND token = 'Ip7Chi6E0K64Y5v7JzHMwutsb8cVq5SJG6M228prDDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}