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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47db1f66c02d1f4f61e7819ba115662754dcec2d82f4deb3eb5b00b476637a9a' 
  AND token = 'pQnbpio/ki0gNyru/rObZmpEn5FT+GDZpPzAHwgEYvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}