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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57d134b25293e11576ad6d6644c6d00d3411a298888807f9e020d2de9b9e8af3' 
  AND token = 'KFV48tYUUsXU6KUv6dtymNS2QgKfaxItkjQP90mj5fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}