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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce257276c22e5476d7cc7e46921a21c13a84a86141aba4bfa5ccf6e08e464daa' 
  AND token = 'OhYMJyg4M1Rde7x3+V5N9RcEMeyAPfUkJqy7fAj9ays=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}