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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72b09c9d3e2cc7246a5c7c3c71d35730cbb1a704772adc2f2ed890208a92429' 
  AND token = 'gILuOSF4t0u7JcVzlKdrDOTK0cKVKipEgsw6EaE9dso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}