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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1e26f44e2c178c5b01888f833d9ff0f0c921fbc25f2d732968757236375cf64' 
  AND token = '7AVJeqrL2XMA4Wcfqy+laFALYJDnXOS+ygWYP68FOmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}