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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7341ca8d67d5145c6a3653dd75d7ffa2c3857cf2c9de4da6e6c222e754a2d79b' 
  AND token = 'dF4kXi9Iy1tsYGGUpMQoFkyNN9A9XQk4miF1woSw5TM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}