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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73a9e698d502edd2eec9cbdaac9399816090e75d36f23ec998e26db604452522' 
  AND token = '0f0ji1IagD+ltDqXHxwBdHdFFHx3pKeCgXC/0U43pXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}