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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '661b58839e99a1307d964e401480fcbf4c9badbdffb3975c9e33678e0d5e493e' 
  AND token = '+brm3GL1FvXYk7MUezRF+fK7Wm+VeoF/Oliwp8xEEak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}