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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c0fc031a8ade2c6ad2c113b9c9f037ba2f798fd1406d5e72f56101fc9594951' 
  AND token = 'vVC9dcGeZpxI1F+WgiOF9nahGZEhbYRifWyRLTQrkhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}