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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cde690d3d8747a312355c090d170bae3f2c002e7117c01089ebbe40c4d40c7de' 
  AND token = 'HiZdCaTCoWm78oLE4BBrR1W1CZYJ/QlRQQ9j76AdBco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}