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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25043f214095b5ff85b402578d88044551aeff054117fde0d14c2089d3c123d3' 
  AND token = '+lkgIwn2rPZxcLQ8S3m2dQgQLMBlRgO9DGNVY3W3KoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}